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|
Total n=77
| |
N
|
D
|
S
|
|---|
|
SMI
|
kg/m2
|
7.1±0.7
|
7.0±0.8
|
5.8±0.6+#
|
|
Grip strength
|
kg
|
29.0±7.5
|
17.5±5.2*
|
10.6±5.2+#
|
|
Gait speed
|
m/sec
|
1.09±0.21
|
1.04±0.27
|
0.64±0.12+#
|
|
c-miR-486
|
ratio
|
1.09±0.04
|
1.08±0.04
|
1.06±0.04+#
|
|
c-miR-133a
|
ratio
|
1.28 ±0.08
|
1.28±0.07
|
1.26±0.05
|
|
c-miR-146a
|
ratio
|
1.24±0.06
|
1.23±0.06
|
1.20 ±0.05#
|
|
c-miR-21
|
ratio
|
1.19±0.05
|
1.17±0.05
|
1.16±0.04
|
|
Female n=36
|
|
SMI
|
kg/m2
|
6.9±0.7
|
7.0±0.6
|
5.6±0.61+#
|
|
Grip strength
|
kg
|
28.3±8.6
|
17.8±5.6*
|
10.0±4.5+#
|
|
Gait speed
|
m/sec
|
1.22±0.24
|
1.10±0.24
|
0.61±0.13+#
|
|
c-miR-486
|
ratio
|
1.08±0.03
|
1.08±0.04
|
1.08±0.05
|
|
c-miR-133a
|
ratio
|
1.28 ±0.05
|
1.28±0.06
|
1.28±0.1
|
|
c-miR-146a
|
ratio
|
1.22±0.06
|
1.22±0.06
|
1.22 ±0.05
|
|
c-miR-21
|
ratio
|
1.18±0.05
|
1.17±0.05
|
1.18±0.05
|
|
Male n=41
|
|
SMI
|
kg/m2
|
7.2±0.8
|
7.0±0.9
|
6.0±0.6+#
|
|
Grip strength
|
kg
|
30.1±6.9
|
17.2±4.9*
|
11.1±5.9+#
|
|
Gait speed
|
m/sec
|
0.91±0.13
|
1.06±0.12
|
0.67±0.11+#
|
|
c-miR-486
|
ratio
|
1.10±0.05
|
1.08±0.04
|
1.04±0.05
|
|
c-miR-133a
|
ratio
|
1.28±0.06
|
1.28±0.11
|
1.24±0.05
|
|
c-miR-146a
|
ratio
|
1.26±0.08
|
1.23±0.03
|
1.18±0.07
|
|
c-miR-21
|
ratio
|
1.20±0.06
|
1.18±.003
|
1.14±0.07
|
- N normal group (n=24), DS decrease of strength group (n=35), S sarcopenia group (n=18), SMI skeletal muscle mass index, Values are mean ± standard deviation. *P < 0.05, N vs. D; +P < 0.05, D vs. S; # P < 0.05, N vs. S
