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Table 1 Characteristics of patients with ischemic and hemorrhagic types of acute stroke compared to those without stroke

From: Incidence, characteristics and clinical relevance of acute stroke in old patients hospitalized with COVID-19

Characteristics Total No stroke Stroke p value
  N = 265 N = 254 N = 11  
Age, years 85.9 ± 6.5 85.8 ± 6.6 87.1 ± 4.5 0.398
Length of stay in acute care, days 12.6 ± 7.7 12.7 ± 7.7 11.9 ± 7.8 0.645
Male sex 114 (43.0%) 109 (42.9%) 5 (45.5%) > 0.999
Help in ADL/IADL 127 (47.9%) 121 (47.6%) 6 (54.5%) 0.762
Mortality 85 (32.1%) 82 (32.3%) 3 (27.3%) > 0.999
Number of medications 7.4 ± 4.1 7.4 ± 4.1 6.4 ± 3.0 0.286
Heart failure 93 (36.5%) 90 (36.9%) 3 (27.3%) 0.750
COPD 30 (11.4%) 27 (10.7%) 3 (27.3%) 0.117
Active smoking 15 (5.7%) 12 (4.8%) 3 (27.3%) 0.019
Kidney disease 74 (28.2%) 70 (27.9%) 4 (36.4%) 0.510
Diabetes under treatment 63 (24.0%) 60 (23.9%) 3 (27.3%) 0.728
Cognitive impairment 134 (51.0%) 127 (50.4%) 7 (63.6%) 0.540
Active neoplasia 23 (8.8%) 22 (8.8%) 1 (9.1%) > 0.999
History of coronary disease 36 (13.6%) 35 (13.8%) 1 (9.1%) > 0.999
History of stroke 40 (15.2%) 35 (13.8%) 5 (45.5%) 0.014
Atrial fibrillation 61 (23.1%) 58 (22.9%) 3 (27.3%) 0.719
Hypertension 187 (70.8%) 179 (70.8%) 8 (72.7%) > 0.999
Dyslipidemia 91 (34.5%) 84 (33.2%) 7 (63.6%) 0.051
PE or DVT 6 (2.26%) 6 (2.36%) 0 > 0.999
BMI, kg × m−2 24.8 ± 6.4 24.9 ± 6.4 20.7 ± 3.5 0.002
Asymptomatic 22 (8.5%) 19 (7.7%) 3 (27.3%) 0.056
Cough 160 (61.5%) 155 (62.2%) 5 (45.5%) 0.344
Dyspnea 99 (38.1%) 95 (38.2%) 4 (36.4%) > 0.999
Tiredness 126 (48.5%) 125 (50.2%) 1 (9.1%) 0.010
Falls 30 (11.5%) 28 (11.2%) 2 (18.2%) 0.369
Delirium 53 (20.4%) 49 (19.7%) 4 (36.4%) 0.242
FIM (18–126) 71.8 ± 29.4 72.2 ± 29.7 62.1 ± 20.7 0.222
CIRS-G (0–56) 19.1 ± 6.2 19.0 ± 6.3 20.3 ± 2.3 0.170
CFS ≥5 190 (80.9%) 182 (80.5%) 8 (88.9%) > 0.999
PSI (0–395) 126.1 ± 53.9 125.9 ± 54.7 130.7 ± 32.3 0.650
CURB-65     0.960
 1–2 168 (63.6%) 161 (63.6%) 7 (63.6%)  
 3 86 (32.6%) 82 (32.4%) 4 (36.4%)  
 4–5 10 (3.8%) 10 (4.0%) 0 (0.0%)  
FiO2, % 26.4 ± 9.6 26.5 ± 9.6 24.2 ± 7.5 0.394
Lymphocytes, G/l 1.2 ± 1.3 1.2 ± 1.3 1.0 ± 0.5 0.361
Pro-brain natriuretic peptide, pg/ml 5904.0 ± 10,525.5 5129.4 ± 8216.0 25,657.8 ± 32,622.7 0.297
C-reactive protein, mg/l 67.8 ± 72.0 66.4 ± 71.1 98.1 ± 89.1 0.270
  1. Abbreviations: ADL activities of daily living, IADL instrumental activities of daily living, COPD chronic obstructive pulmonary disease, PE pulmonary embolism, DVT deep vein thrombosis, BMI body mass index, FIM Functional Independence Measure, CIRS-G Cumulative Illness Rating Scale-Geriatric, CFS Clinical Frailty Score, PSI pneumonia severity index, FiO2 Fraction of inspired oxygen